Matti Aapro Selected Research

Palonosetron (Aloxi)

1/2022	Netupitant-palonosetron (NEPA) for Preventing Chemotherapy-induced Nausea and Vomiting: From Clinical Trials to Daily Practice.
3/2020	Efficacy of olanzapine, neurokinin-1 receptor antagonists, and thalidomide in combination with palonosetron plus dexamethasone in preventing highly emetogenic chemotherapy-induced nausea and vomiting: a Bayesian network meta-analysis.
12/2019	Impact of dexamethasone-sparing regimens on delayed nausea caused by moderately or highly emetogenic chemotherapy: a meta-analysis of randomised evidence.
12/2019	One-Day Versus Three-Day Dexamethasone in Combination with Palonosetron for the Prevention of Chemotherapy-Induced Nausea and Vomiting: A Systematic Review and Individual Patient Data-Based Meta-Analysis.
10/2019	Do we still need to study palonosetron for chemotherapy-induced nausea and vomiting? A cumulative meta-analysis.
4/2019	Preventing chemotherapy-induced nausea and vomiting with netupitant/palonosetron, the first fixed combination antiemetic: current and future perspective.
4/2019	Timing flexibility of oral NEPA, netupitant-palonosetron combination, administration for the prevention of chemotherapy-induced nausea and vomiting (CINV).
6/2017	Efficacy of NEPA (netupitant/palonosetron) across multiple cycles of chemotherapy in breast cancer patients: A subanalysis from two phase III trials.
1/2017	NEPA, a fixed oral combination of netupitant and palonosetron, improves control of chemotherapy-induced nausea and vomiting (CINV) over multiple cycles of chemotherapy: results of a randomized, double-blind, phase 3 trial versus oral palonosetron.
1/2015	Review of oral fixed-dose combination netupitant and palonosetron (NEPA) for the treatment of chemotherapy-induced nausea and vomiting.

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Matti Aapro Research Topics

Disease

70	Neoplasms (Cancer) 01/2022 - 01/2002
48	Vomiting 01/2022 - 01/2004
47	Nausea 01/2022 - 01/2004
29	Breast Neoplasms (Breast Cancer) 01/2022 - 01/2002
18	Anemia 01/2019 - 10/2006
15	Febrile Neutropenia 01/2022 - 02/2008
11	Neutropenia 01/2022 - 06/2010
10	Chemotherapy-Induced Febrile Neutropenia 06/2019 - 05/2010
9	Neoplasm Metastasis (Metastasis) 06/2019 - 03/2007
4	Fatigue 01/2021 - 08/2014
4	Prostatic Neoplasms (Prostate Cancer) 10/2017 - 04/2012
4	Osteonecrosis (Kienbock's Disease) 10/2012 - 03/2007
3	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 01/2017
3	Alopecia (Baldness) 01/2021 - 04/2016
3	Multiple Myeloma 04/2012 - 01/2010
2	COVID-19 01/2022 - 01/2021
2	Hypersensitivity (Allergy) 01/2021 - 01/2020
2	Infections 01/2021 - 10/2017
2	Dyspnea (Shortness of Breath) 01/2021 - 06/2019
2	Hemorrhage 01/2021 - 04/2011
2	Hematologic Neoplasms (Hematological Malignancy) 12/2019 - 03/2019
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 07/2019 - 05/2007
2	Disease Progression 06/2019 - 01/2002
2	Hypertension (High Blood Pressure) 06/2019 - 05/2011
2	Non-Hodgkin Lymphoma (Lymphosarcoma) 09/2018 - 03/2018
2	Iron Deficiencies 12/2015 - 01/2014
2	Osteoporosis 08/2014 - 04/2012
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2021
1	Sepsis (Septicemia) 01/2021
1	Injection Site Reaction 01/2021
1	Anaphylaxis (Anaphylactic Shock) 01/2020

Drug/Important Bio-Agent (IBA)

23	AntiemeticsIBA 01/2022 - 01/2004
20	Biosimilar PharmaceuticalsIBA 06/2020 - 03/2011
14	Palonosetron (Aloxi)FDA Link 01/2022 - 01/2004
14	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2021 - 02/2003
14	AnthracyclinesIBA 01/2021 - 01/2002
13	Dexamethasone (Maxidex)FDA LinkGeneric 01/2021 - 02/2005
13	Filgrastim (Neupogen)FDA Link 06/2020 - 03/2011
9	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 01/2022 - 02/2008
9	HematinicsIBA 01/2019 - 02/2007
6	netupitantIBA 01/2022 - 01/2015
6	5-HT3 Serotonin Receptors (5 HT3 Receptor)IBA 01/2021 - 01/2004
6	Cisplatin (Platino)FDA LinkGeneric 01/2021 - 01/2008
5	Hormones (Hormone)IBA 01/2022 - 04/2011
5	Neurokinin-1 Receptor AntagonistsIBA 01/2021 - 04/2016
5	Epoetin Alfa (Epogen)FDA Link 01/2019 - 01/2014
5	Aprepitant (Emend)FDA Link 07/2014 - 01/2004
5	Diphosphonates (Bisphosphonates)IBA 04/2012 - 03/2007
5	Pharmaceutical PreparationsIBA 04/2012 - 01/2004
5	epoetin betaIBA 11/2009 - 01/2004
4	pegfilgrastim (Neulasta)FDA Link 06/2020 - 06/2010
4	taxaneIBA 06/2019 - 01/2004
4	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2017 - 06/2005
4	IronIBA 11/2016 - 01/2014
4	Zoledronic Acid (Zometa)FDA Link 04/2012 - 03/2007
3	Olanzapine (Zyprexa)FDA Link 08/2021 - 03/2020
3	Colony-Stimulating Factors (Colony Stimulating Factor)IBA 06/2019 - 05/2010
3	Serotonin (5 Hydroxytryptamine)IBA 01/2017 - 07/2005
3	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2017 - 02/2003
3	Granisetron (Kytril)FDA LinkGeneric 08/2016 - 01/2004
3	Denosumab FDA Link 04/2012 - 01/2010
3	Docetaxel (Taxotere)FDA Link 10/2011 - 01/2002
3	Proteins (Proteins, Gene)FDA Link 07/2010 - 02/2007
2	Carboplatin (JM8)FDA LinkGeneric 01/2021 - 08/2016
2	Paclitaxel (Taxol)FDA LinkGeneric 06/2019 - 10/2011
2	Vinorelbine (Navelbine)FDA LinkGeneric 06/2019 - 04/2012
2	Biological ProductsIBA 11/2018 - 01/2017
2	AntibodiesIBA 10/2017 - 01/2017
2	RadiopharmaceuticalsIBA 01/2017 - 05/2012
2	Substance PIBA 01/2017 - 06/2005
2	rolapitantIBA 01/2017 - 08/2016
2	Hemoglobins (Hemoglobin)IBA 04/2013 - 10/2006
2	CreatinineIBA 05/2012 - 03/2012
2	Aromatase InhibitorsIBA 04/2011 - 07/2007
2	Pamidronate (Aredia)FDA LinkGeneric 01/2010 - 03/2007
2	Vincristine (Oncovin)FDA LinkGeneric 01/2009 - 02/2003
2	liposomal doxorubicin (Doxil)FDA Link 04/2008 - 01/2007
2	Erythropoietin FDA Link 02/2008 - 01/2004
2	Capecitabine (Xeloda)FDA Link 01/2002 - 01/2002
1	phytobacteriomycin (PBM)IBA 01/2022
1	human ERBB2 proteinIBA 01/2022
1	Phenobarbital (Luminal)FDA Link 01/2022
1	PlatinumIBA 01/2021
1	Cyclin-Dependent Kinase 4IBA 01/2021
1	trilaciclibIBA 01/2021
1	Topotecan (Hycamtin)FDA LinkGeneric 01/2021
1	Etoposide (VP 16)FDA LinkGeneric 01/2021
1	Thalidomide (Thalomid)FDA Link 03/2020
1	fosaprepitant FDA Link 01/2020

Therapy/Procedure

94	Drug Therapy (Chemotherapy) 01/2022 - 01/2002
36	Therapeutics 01/2022 - 01/2002
6	Radiotherapy 01/2017 - 01/2002
4	Adjuvant Chemotherapy 06/2019 - 06/2005
3	Palliative Care (Palliative Therapy) 01/2021 - 12/2017
2	Chemoradiotherapy 01/2019 - 01/2008
2	Activities of Daily Living (ADL) 12/2017 - 10/2017
2	Castration 10/2017 - 01/2017
2	Combination Drug Therapy (Combination Chemotherapy) 01/2008 - 07/2004
1	Ambulatory Care (Outpatient Care) 01/2022
1	Length of Stay 01/2022